ORAK H�CRE HASTALI�I OLAN �K� HASTADA BACAK �LSER�, PULMONER H�PERTANS�YON VE SESS�Z SEREBRAL �NFARKT

SERARSLAN, Gamze; MELEK, �smet Murat; AKG�L, Ferit; SERARSLAN, Yurdal; DUMAN, Ta�k�n

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Volume : 12 Issue : 3 Year : 2023

Online Makale G�nder 29/3Son Say� Erken Bask� Ar�iv Pop�ler Makaleler

Yay�n Hakk� Devir Formu

Turkish Journal of Cerebrovascular Diseases

ORAK H�CRE HASTALI�I OLAN �K� HASTADA BACAK �LSER�, PULMONER H�PERTANS�YON VE SESS�Z SEREBRAL �NFARKT [T�rk Beyin Damar Hast Derg]

T�rk Beyin Damar Hast Derg. 2006; 12(3): 89-91

ORAK H�CRE HASTALI�I OLAN �K� HASTADA BACAK �LSER�, PULMONER H�PERTANS�YON VE SESS�Z SEREBRAL �NFARKT

Gamze SERARSLAN¹, �smet Murat MELEK¹, Ferit AKG�L¹, Yurdal SERARSLAN¹, Ta�k�n DUMAN¹
Mustafa Kemal University, Faculty of Medicine, Department of Dermatology, Neurology, Cardiology and Neurosurgery Antakya/Hatay, TURKEY

Orak h�cre hastal�� kal�tsal bir hemoglobinopatidir ve deoksijene olan HbS�in polimerizasyonu hastal��n klinik bulgular�na neden olur. Sessiz serebral infarkt� olan orak h�cre hastalar�nda, beyin MR bulgular� normal olan hastalara g�re inme riski 14 kat daha fazlad�r. Bacak �lseri, pulmoner hipertansiyon ve sessiz serebral infarkt� olan ve tek semptomun bacak �lseri oldu�u orak h�cre hastal�� olan iki hastay� sunmaktay�z.

Anahtar Kelimeler: Orak h�cre hastal��, bacak �lseri, sessiz serebral infarkt, pulmoner hipertansiyon

LEG ULCER, PULMONARY HYPERTENSION AND SILENT CEREBRAL INFARCT IN TWO PATIENTS WITH SICKLE CELL DISEASE

Gamze SERARSLAN¹, �smet Murat MELEK¹, Ferit AKG�L¹, Yurdal SERARSLAN¹, Ta�k�n DUMAN¹

Sickle cell disease is an inherited hemoglobinopathy and polymerization of deoxygenated HbS lead to clinical manifestations of the disease. The stroke rate in sickle cell disease patients with silent cerebral infarct is 14-fold higher than in those with normal MRI. We present two patients of sickle cell disease with leg ulcer, pulmonary hypertension and silent cerebral infarct and the only symptom was the leg ulcer.

Keywords: Sickle cell disease, leg ulcer, silent cerebral infarct, pulmonary hypertension

Gamze SERARSLAN, �smet Murat MELEK, Ferit AKG�L, Yurdal SERARSLAN, Ta�k�n DUMAN. LEG ULCER, PULMONARY HYPERTENSION AND SILENT CEREBRAL INFARCT IN TWO PATIENTS WITH SICKLE CELL DISEASE. T�rk Beyin Damar Hast Derg. 2006; 12(3): 89-91
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ORAK H�CRE HASTALI�I OLAN �K� HASTADA BACAK �LSER�, PULMONER H�PERTANS�YON VE SESS�Z SEREBRAL �NFARKT

LEG ULCER, PULMONARY HYPERTENSION AND SILENT CEREBRAL INFARCT IN TWO PATIENTS WITH SICKLE CELL DISEASE