Türk Beyin Damar Hast Derg. 2012; 18(2): 46-48 | DOI: 10.5505/tbdhd.2012.36855

Antifosfolipit antikor sendromlu hastada intraserebral hemoraji

Sultan Çaðýrýcý¹, Abdulkadir Koçer², Levent Gül¹, Ülkü Türk Börü¹, Talip Asil^2
1Dr. Lütfü Kýrsar Eðitim Hastanesi Nöroloji Bölümü, Ýstanbul
²Bezmialem Vakýf Üniversitesi Týp Fakültesi Nöroloji Anabilim Dalý, Ýstanbul

GÝRÝÞ: Lupus antikoagulaný pozitif olan hastalarda digger bilinen risk faktörleri ile birlikte iskemik beyin lezyonlarý ve subdural hematom sýklýðý artmýþtýr. Subdural hematom ile antifosfolipid sendrom birlikteliðini tanýmlayan pek çok yazý bulunmaktadýr ancak intraaksiyal kanamalar antifosfolipid antikor sendromunun nadir görülen bir komplikasyonudur.
OLGU: Bu yazýda sað santral fasial parezi, sað hemiparezi, motor afazi ve ptoz ile baþvuran 37 yaþýnda erkek hastayý sunduk. BT ve MRI sol frontoparietal bölgede geniþ intraserebral kanama ve sað hemisferde küçük hemoraji odaklarýný göstermekteydi. Tek pozitif labaratuar bulgusu antifosfolipid antikorlarýn pozitif olmasý idi. Mevcut bulgularla hastanýn antifosfolipit antikorlarla iliþkili intraserebral hematom olarak düþündük
TARTIÞMA: Bu olgu sunumunda genç bir hastada antifosfolipit antikorlarla iliþkili olarak damar frajilitesinin artmasý veya trombosit disfonksiyonuna baðlý nadir görülen bir durum olan intraserebral hematom olgusunu bildirdik.

Anahtar Kelimeler: Antiphospholipid syndrome, intracerebral bleeding, risk factor.

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Intracerebral hemorrhage in a case of antiphospholipid antibody syndrome

Sultan Çaðýrýcý¹, Abdulkadir Koçer², Levent Gül¹, Ülkü Türk Börü¹, Talip Asil^2
1Dr. Lütfü Kýrdar Education Hospital, Department Of Neurology, Ýstanbul
²Bezmialem Vakýf University Medical Faculty Neurology Department, Ýstanbul

BACKGROUND AND PURPOSE: The patients with lupus anticoagulants may have an increased risk for the development of ischemic brain lesions and subdural hematoma in the presence of other known risk factors. There are lots of reports related to antiphospholipid syndrome with subdural hematoma, but intra-axial bleeding is a rare complication.
CASE DESCRIPTION: We report a 37-year-old man with ptosis, central typed facial palsy, hemiparesis on the right side and motor aphasia. A CT scan and MRI showed a large cerebral hematoma located in the left fronto-parietal region and other foci of hemorrhage on the right hemisphere. Only persistently abnormal finding in laboratory studies was positive for anti-phospholipid antibodies. Based on above findings we concluded that anti-phospholipid antibodies have resulted in intracerebral hemorrhage.
CONCLUSION: In the present case, we report and point that hemorrhagic complication in young patients with anti-phospholipid antibody syndrome associated with fragility of the vessels and/or platelet dysfunction is another and rare cause of intracerebral bleeding.

Keywords: Antifosfolipid antikor sendromu, intraserebral hematom, risk faktörleri.

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ATIF KOPYALA